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There are several matches for 'surface presentation of antigens protein'.
Please select one from the list below and press Continue to proceed.
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906 matches
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organism
protein
1)
Homo sapiens
CD1A - T-cell
surface
glycoprotein CD1a;
Antigen
-
presenting
protein
that binds self and non-self lipid and glycolipid
antigens
and
presents
them to T-cell receptors on natural killer T-cells.
[a.k.a. BAG35786.1, AAA51932.1, Q9Y5M5]
2)
Homo sapiens
CD1B - T-cell
surface
glycoprotein CD1b;
Antigen
-
presenting
protein
that binds self and non-self lipid and glycolipid
antigens
and
presents
them to T-cell receptors on natural killer T-cells.
[a.k.a. 5L2J, XP_011508421.1, NM_001764.3]
3)
Homo sapiens
CD1C - T-cell
surface
glycoprotein CD1c;
Antigen
-
presenting
protein
that binds self and non-self lipid and glycolipid
antigens
and
presents
them to T-cell receptors on natural killer T-cells.
[a.k.a. CD1C-202, 911, CAG33361.1]
4)
Homo sapiens
CD8A - T-cell
surface
glycoprotein CD8 alpha chain; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The
antigens
presented
by class I peptides are derived from cytosolic
proteins
while class II derived from extracellular
proteins
. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I
proteins
presented
by
antigen
presenting
cells (APCs). In turn, recruits the Sr [...]
[a.k.a. Q4ZG17, hsa:925, CD8]
5)
Homo sapiens
HLA-DRA - HLA class II histocompatibility
antigen
, DR alpha chain; Binds peptides derived from
antigens
that access the endocytic route of
antigen
presenting
cells (APC) and
presents
them on the cell
surface
for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides
presented
by MHC class II molecules are generated mostly by degradation of
proteins
that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous
antigens
that have been endocytosed by the APC are thus readily available for pre [...]
[a.k.a. 1T5W, 3122, 2FSE]
6)
Homo sapiens
HLA-DQA2 - HLA class II histocompatibility
antigen
, DQ alpha 2 chain; Binds peptides derived from
antigens
that access the endocytic route of
antigen
presenting
cells (APC) and
presents
them on the cell
surface
for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides
presented
by MHC class II molecules are generated mostly by degradation of
proteins
that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous
antigens
that have been endocytosed by the APC are thus readily available for p [...]
[a.k.a. HLA-DQA1, KY500360, CAM26196.1]
7)
Homo sapiens
HLA-DQB1 - HLA class II histocompatibility
antigen
, DQ beta 1 chain; Binds peptides derived from
antigens
that access the endocytic route of
antigen
presenting
cells (APC) and
presents
them on the cell
surface
for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides
presented
by MHC class II molecules are generated mostly by degradation of
proteins
that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous
antigens
that have been endocytosed by the APC are thus readily available for pr [...]
[a.k.a. Q30095, ENSP00000308869, UPI000012C0BC]
8)
Homo sapiens
HLA-DRB5 - HLA class II histocompatibility
antigen
, DR beta 5 chain; Binds peptides derived from
antigens
that access the endocytic route of
antigen
presenting
cells (APC) and
presents
them on the cell
surface
for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides
presented
by MHC class II molecules are generated mostly by degradation of
proteins
that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous
antigens
that have been endocytosed by the APC are thus readily available for pr [...]
[a.k.a. 3127, CAA70524.1, R-HSA-202424]
9)
Homo sapiens
HLA-DPA1 - HLA class II histocompatibility
antigen
, DP alpha 1 chain; Binds peptides derived from
antigens
that access the endocytic route of
antigen
presenting
cells (APC) and
presents
them on the cell
surface
for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides
presented
by MHC class II molecules are generated mostly by degradation of
proteins
that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous
antigens
that have been endocytosed by the APC are thus readily available for p [...]
[a.k.a. MH920368, NM_033554, NP_001229453]
10)
Homo sapiens
HLA-DQB2 - HLA class II histocompatibility
antigen
, DQ beta 2 chain; Binds peptides derived from
antigens
that access the endocytic route of
antigen
presenting
cells (APC) and
presents
them on the cell
surface
for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides
presented
by MHC class II molecules are generated mostly by degradation of
proteins
that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous
antigens
that have been endocytosed by the APC are thus readily available for pr [...]
[a.k.a. DQB2_HUMAN, R-HSA-202424, NP_001185787]
11)
Homo sapiens
HLA-DPB1 - HLA class II histocompatibility
antigen
, DP beta 1 chain; Binds peptides derived from
antigens
that access the endocytic route of
antigen
presenting
cells (APC) and
presents
them on the cell
surface
for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides
presented
by MHC class II molecules are generated mostly by degradation of
proteins
that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous
antigens
that have been endocytosed by the APC are thus readily available for pr [...]
[a.k.a. HPA058509, Q95HC1, O98217]
12)
Homo sapiens
CD4 - T-cell
surface
glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The
antigens
presented
by class II peptides are derived from extracellular
proteins
while class I peptides are derived from cytosolic
proteins
. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II
presented
by
antigen
presenting
cells (APCs). In turn, recruits the Src kina [...]
[a.k.a. R-HSA-162587, 3JCC, 4Q6I]
13)
Homo sapiens
CD79A - B-cell
antigen
receptor complex-associated
protein
alpha chain; Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of
antigen
to the B- cell
antigen
receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and
antigen
presentation
. Also required for BCR
surface
expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts wit [...]
[a.k.a. R-HSA-983705, MB1, S46706]
14)
Homo sapiens
CD209 - CD209
antigen
; Pathogen-recognition receptor expressed on the
surface
of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane
surface
and the pathogen-derived
antigens
are
presented
to resting T-cells via MHC class II
proteins
to initiate the adaptive immune response. (Microbial infection) Acts as an attachment receptor for HIV- 1 and HIV-2. (Microbial infection) Acts as an attachment receptor for Cytomegal [...]
[a.k.a. ENST00000602261.5, ENST00000593821, CCDS45952]
15)
Homo sapiens
B2M - Beta-2-microglobulin form pI 5.3; Component of the class I major histocompatibility complex (MHC). Involved in the
presentation
of peptide
antigens
to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell
surface
(total
protein
levels do not change), probably leading to defects in class I
antigen
presentation
. Belongs to the beta-2-microglobulin family.
[a.k.a. 4QOK, 1HLA, 1T20]
16)
Homo sapiens
SIRPG - Signal-regulatory
protein
gamma; Probable immunoglobulin-like cell
surface
receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on
antigen
-
presenting
cells results in enhanced
antigen
- specific T-cell proliferation and costimulates T-cell activation.
[a.k.a. CCDS13020.2, R-HSA-202733, AB042624]
17)
Homo sapiens
CD3D - T-cell
surface
glycoprotein CD3 delta chain; Part of the TCR-CD3 complex
present
on T-lymphocyte cell
surface
that plays an essential role in adaptive immune response. When
antigen
presenting
cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family
protein
tyrosine kinases LCK and FYN, resulting in the activation of [...]
[a.k.a. P04234, 915, BC070321]
18)
Homo sapiens
CD3E - T-cell
surface
glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex
present
on T-lymphocyte cell
surface
that plays an essential role in adaptive immune response. When
antigen
presenting
cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family
protein
tyrosine kinases LCK and FYN, resulting in the activation o [...]
[a.k.a. CD3E-202, R-HSA-202424, CHEMBL1975]
19)
Homo sapiens
CD247 - T-cell
surface
glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex
present
on T-lymphocyte cell
surface
that plays an essential role in adaptive immune response. When
antigen
presenting
cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family
protein
tyrosine kinases LCK and FYN, resulting in the activation of d [...]
[a.k.a. AL031733, TCRZ, ENST00000476733.5]
20)
Homo sapiens
CD3G - T-cell
surface
glycoprotein CD3 gamma chain; Part of the TCR-CD3 complex
present
on T-lymphocyte cell
surface
that plays an essential role in adaptive immune response. When
antigen
presenting
cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family
protein
tyrosine kinases LCK and FYN, resulting in the activation of [...]
[a.k.a. uc001psu.3, ENST00000533462, NM_000073.2]
906 matches
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